| Applications: | SDS-PAGE, Denatured |
| Species Reactivity: | Mouse |
| MW: | 20.4 kDa (179aa) |
| Purity: | > 85% by SDS - PAGE |
| Description: | IL-1a is produced by activated macrophages, stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. This protein is involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Recombinant mouse IL1a protein, fused to His-tag at N-terminus, was expressed in E. coli. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSSAPYTYQ SDLRYKLMKL VRQKFVMNDS LNQTIYQDVD KHYLSTTWLN DLQQEVKFDM YAYSSGGDDS KYPVTLKISD SQLFVSAQGE DQPVLLKELP ETPKLITGSE TDLIFFWKSI NSKNYFTSAA YPELFIATKE QSRVHLARGL PSMTDFQIS |
| Synonym: | Interleukin-1 alpha precursor, Il-1a, IL-1 alpha, Il-1a, Interleukin 1 alpha |
| Ascension Number: | P01582 |
| NCBI EntrezGene: | NP_034684 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
