| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 20.3kDa (182aa) confirmed by MALDI-TOF |
| Purity: | > 85% by SDS - PAGE |
| Description: | M6PR is a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. This protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. Recombinant human M6PR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSTEEKTCD LVGEKGKESE KELALVKRLK PLFNKSFEST VGQGSDTYIY IFRVCREAGN HTSGAGLVQI NKSNGKETVV GRLNETHIFN GSNWIMLIYK GGDEYDNHCG KEQRRAVVMI SCNRHTLADN FNPVSEERGK VQDCFYLFEM DSSLACSPEI SH |
| Synonym: | Cation-dependent mannose-6-phosphate receptor isoform 1, CD-MPR, MPR 46, MPR-46, MPR46, SMPR |
| Ascension Number: | P20645 |
| NCBI EntrezGene: | NP_002346 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
