| Applications: | SDS-PAGE, Denatured |
| Species Reactivity: | Human |
| MW: | 35.3 kDa (308aa) |
| Purity: | > 85% by SDS - PAGE |
| Description: | Centromere protein P, also known as CENPP, is component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. This protein may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Recombinant human CENPP protein, fused to His-tag at N-terminus, was expressed in E. coli. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MDAELAEVRA LQAEIAALRR ACEDPPAPWE EKSRVQKSFQ AIHQFNLEGW KSSKDLKNQL GHLESELSFL STLTGINIRN HSKQTEDLTS TEMTEKSIRK VLQRHRLSGN CHMVTFQLEF QILEIQNKER LSSAVTDLNI IMEPTECSEL SEFVSRAEER KDLFMFFRSL HFFVEWFEYR KRTFKHLKEK YPDAVYLSEG PSSCSMGIRS ASRPGFELVI VWRIQIDEDG KVFPKLDLLT KVPQRALELD KNRAIETAPL SFRTLVGLLG IEAALESLIK SLCAEENN |
| Synonym: | Centromere protein P, CENP-P, RP11-19J3.3 |
| Ascension Number: | Q6IPU0 |
| NCBI EntrezGene: | NP_001012267 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
