| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 39.1 kDa(347aa) confirmed by MALDI-TOF |
| Purity: | > 90% by SDS - PAGE |
| Description: | FAM49B has been provisionally designated FAM49B pending further characterization. In a recent genome-wide transcriptional analysis, It identified a gene signature for multiple sclerosis (MS), which reverted back to normal during pregnancy. Reversion was particularly evident for 7 genes: SOCS2, TNFAIP3, NR4A2, CXCR4, POLR2J, FAM49B, and STAG3L1, most of which encode negative regulators of inflammation. Recombinant human FAM49B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGNLLKV LTCTDLEQGP NFFLDFENAQ PTESEKEIYN QVNVVLKDAE GILEDLQSYR GAGHEIREAI QHPADEKLQE KAWGAVVPLV GKLKKFYEFS QRLEAALRGL LGALTSTPYS PTQHLEREQA LAKQFAEILH FTLRFDELKM TNPAIQNDFS YYRRTLSRMR INNVPAEGEN EVNNELANRM SLFYAEATPM LKTLSDATTK FVSENKNLPI ENTTDCLSTM ASVCRVMLET PEYRSRFTNE ETVSFCLRVM VGVIILYDHV HPVGAFAKTS KIDMKGCIKV LKDQPPNSVE GLLNALRYTT KHLNDETTSK QIKSMLQ |
| Synonym: | Protein FAM49B, Protein FAM49B, BM-009, L1 |
| Ascension Number: | Q9NUQ9 |
| NCBI EntrezGene: | NP_057707 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
