| Applications: | SDS-PAGE, Denatured |
| Species Reactivity: | Human |
| MW: | 19.9 kDa (172aa) |
| Purity: | > 90% by SDS - PAGE |
| Description: | Neurotensin, also known as NTS, is a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. Recombinant human NTS protein, fused to His-tag at N-terminus, was expressed in E. coli. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSDSEE EMKALEADFL TNMHTSKISK AHVPSWKMTL LNVCSLVNNL NSPAEETGEV HEEELVARRK LPTALDGFSL EAMLTIYQLH KICHSRAFQH WELIQEDILD TGNDKNGKEE VIKRKIPYIL KRQLYENKPR RPYILKRDSY YY |
| Synonym: | Neurotensin neuromedin N, Neurotensin, neuromedin N, NMN-125, NN, NT, NT/N, NTS1 |
| Ascension Number: | P30990 |
| NCBI EntrezGene: | NP_006174 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
