| Applications: | SDS-PAGE |
| Species Reactivity: | Mycobacterium tuberculosis |
| MW: | 11 kDa (104aa) |
| Purity: | > 90% by SDS - PAGE |
| Description: | ESAT6, the 6 kDa early secretory antigenic target of Mycobacterium tuberculosis, is a secretory protein and potent T cell antigen. ESAT6 has been shown to directly bind to the TLR2 receptor, inhibiting downstream signal transduction. Recently it was shown that ESAT6 is very potential as diagnostic for differentiation between the mycobacterial infection and BCG vaccination. Recombinant Mycobacterium tuberculosis CDC1551 ESAT6 protein, fused to His-tag at C-terminus, was expressed in Baculovirus and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: ADPMTEQQWN FAGIEAAASA IQGNVTSIHS LLDEGKQSLT KLAAAWGGSG SEAYQGVQQK WDATATELNN ALQNLARTIS EAGQAMASTE GNVTGMFAHH HHHH |
| Synonym: | Early secretory antigenic target 6 kDa, Early secretory antigenic target, 6 kDa, |
| Ascension Number: | P9WNK6 |
| NCBI EntrezGene: | NP_338543.1 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
