| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 25.7 kDa (227aa) confirmed by MALDI-TOF |
| Purity: | > 90% by SDS - PAGE |
| Description: | GPX3, also known as glutathione peroxidase 3, belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. GPX3 protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. Recombinant human GPX3 (u73C) protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MQSRGQEKSK MDCHGGISGT IYEYGALTID GEEYIPFKQY AGKYVLFVNV ASYCGLTGQY IELNALQEEL APFGLVILGF PCNQFGKQEP GENSEILPTL KYVRPGGGFV PNFQLFEKGD VNGEKEQKFY TFLKNSCPPT SELLGTSDRL FWEPMKVHDI RWNFEKFLVG PDGIPIMRWH HRTTVSNVKM DILSYMRRQA ALGVKRK |
| Synonym: | Glutathione peroxidase 3, GPx-P, GSHPx-3, GSHPx-P |
| Ascension Number: | P22352 |
| NCBI EntrezGene: | NP_002075 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
