| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 19.8 kDa (182aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher) |
| Purity: | > 85% by SDS - PAGE |
| Description: | SNRPC belongs to the u1 small nuclear ribonucleoprotein C family. This protein component of the u1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. This protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. Recombinant human SNRPC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPKFYCD YCDTYLTHDS PSVRKTHCSG RKHKENVKDY YQKWMEEQAQ SLIDKTTAAF QQGKIPPTPF SAPPPAGAMI PPPPSLPGPP RPGMMPAPHM GGPPMMPMMG PPPPGMMPVG PAPGMRPPMG GHMPMMPGPP MMRPPARPMM VPTRPGMTRP DR |
| Synonym: | u1 small nuclear ribonucleoprotein C, u1C, Yhc1 |
| Ascension Number: | P09234 |
| NCBI EntrezGene: | NP_003084 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
