| Applications: | SDS-PAGE, Denatured |
| Species Reactivity: | Human |
| MW: | 15.5 kDa (133aa) |
| Purity: | > 90% by SDS - PAGE |
| Description: | CENPH, also known as centromere protein H, belongs to the centromere protein H family. This protein is component of the CENPA-NAC (nucleosome-associated) complex that plays a central role in assembly of kinetochore proteins. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Recombinant human CENPH protein, fused to His-tag at N-terminus, was expressed in E. coli and denatured using detergent during a conventional chromatography purification process. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MLNKLIMKSQ QESWDLEEKL LDIRKKRLQL KQASESKLLE IQTEKNKQKI DLDSMENSER IKIIRQNLQM EIKITTVIQH VFQNLILGSK VNWAEDPALK EIVLQLEKNV DMM |
| Synonym: | Centromere protein H, CENP H, Centromere protein H, ICEN35, Interphase centromere complex protein 35, Kinetochore protein CENP H, NNF1, MIND kinetochore complex component homolog, PMF1 |
| Ascension Number: | Q9H3R5 |
| NCBI EntrezGene: | NP_075060 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
