| Applications: | SDS-PAGE |
| Species Reactivity: | mouse |
| MW: | 12.4 kDa (109aa), confirmed by MALDI-TOF |
| Purity: | > 95% by SDS - PAGE |
| Description: | S100A8, also known MRP8, is a member of the S100 family, EF-hand superfamily of calcium binding proteins. This protein is localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant mouse S100A8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MPSELEKALS NLIDVYHNYS NIQGNHHALY KNDFKKMVTT ECPQFVQNIN IENLFRELDI NSDNAINFEE FLAMVIKVGV ASHKDSHKE |
| Synonym: | Protein S100-A8, 60B8Ag, AI323541, B8Ag, Caga, CFAg, CP-10, MRP8, p8 |
| Ascension Number: | P27005 |
| NCBI EntrezGene: | NP_038678 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
