| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 12 kDa (112aa), confirmed by MALDI-TOF |
| Purity: | > 90% by SDS - PAGE |
| Description: | Vesicular, overexpressed in cancer, prosurvival protein 1 (VOPP1), also known as Glioblastoma-amplified secreted protein (GASP), has been previously shown to be over-expressed in human glioblastoma multiforme and squamous cell carcinoma. VOPP1 is a key regulator of NF-kappaB signaling, and that high-level, amplification-mediated VOPP1 expression, such as that occurring in tumors with amplified EGFR, could contribute to resistance to apoptosis. Recombinant human VOPP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MRRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK |
| Synonym: | Vesicular overexpressed in cancer prosurvival protein 1, Vesicular, overexpressed in cancer, prosurvival protein 1, ECOP, GASP |
| Ascension Number: | Q96AW1 |
| NCBI EntrezGene: | NP_110423 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
