| Applications: | SDS-PAGE |
| Species Reactivity: | mouse |
| MW: | 12.8 kDa (112aa) confirmed by MALDI-TOF |
| Purity: | > 85% by SDS - PAGE |
| Description: | S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Recombinant mouse S100B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDEDGDGECD FQEFMAFVAM VTTACHEFFE HE |
| Synonym: | Protein S100-B, AI850290, Bpb, Protein S100-B, NEF, S 100 protein beta chain, S 100 protein beta subunit, S100, S100 calcium binding protein B, S100 calcium binding protein beta (neural), S100 calcium binding protein beta chain, S100 protein beta chain, S100B, S100beta |
| Ascension Number: | P50114 |
| NCBI EntrezGene: | NP_033141 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
