| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 20.9 kDa (192aa), confirmed by MALDI-TOF. |
| Purity: | > 95% by SDS - PAGE |
| Description: | BCL2-like protein 2, also known as BCL2L2, is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. BCL2L2 is an anti apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. It is required for normal sperm maturation. Recombinant human BCL2L2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG QVQEWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RT |
| Synonym: | BCL2-like protein 2, Apoptosis regulator Bcl-W, BCLW, BCL2-like protein 2 Apoptosis regulator BCL W, BCL 2 Like 2, Bcl 2 like 2 protein, Bcl 2L2, bcl w, Bcl2 L2, BCL2 like 2, BCL2 like 2 protein, KIAA0271. |
| Ascension Number: | Q92843 |
| NCBI EntrezGene: | NP_004041 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
