| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 14.7 kDa (138aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher) |
| Purity: | > 95% by SDS - PAGE |
| Description: | eIF4E-BP1, also known as eukaryotic translation initiation factor 4E-binding protein 1, is a member of a family of translation repressor proteins. This protein regulates eukaryotic translation initiation factor 4E (eIF4E) activity by preventing its assembly into the eIF4F complex and mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Recombinant EIF4EBP1 protein was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MSGGSSCSQT PSRAIPATRR VVLGDGVQLP PGDYSTTPGG TLFSTTPGGT RIIYDRKFLM ECRNSPVTKT PPRDLPTIPG VTSPSSDEPP MEASQSHLRN SPEDKRAGGE ESQFEMDI |
| Synonym: | Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, 4EBP1, BP-1, MGC4316, PHAS-I, Eukaryotic translation initiation factor 4E-binding protein 1, EIF4EBP1, eukaryotic translation initiation factor 4E binding protein 1, phosphorylated heat- and acid-stable protein regulated by insulin 1, |
| Ascension Number: | Q13541 |
| NCBI EntrezGene: | NP_004086 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
