Ordering Details
Cat Number:	ATGP0291-100ug
Size:	100ug
Concentration:	1 mg/mL (determined by Bradford assay)
Price:	£800.00
Quantity:
Shipping:	£12.00

Annexin A1 [1-346 a.a.], Recombinant Protein

Partner: NKMax Bio (ATGen)

Applications:	SDS-PAGE
Species Reactivity:	Human
MW:	38.7 kDa (346aa), confirmed by MALDI-TOF.
Purity:	> 90% by SDS - PAGE
Description:	Annexin A1, also known as Lipocortin I, belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. It promotes membrane fusion and is also involved in exocytosis. Since Annexin A1 has phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity, this protein may have potential anti-inflammatory activity. The detection of this protein by immunocytochemical means reportedly provides a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia. Recombinant human Annexin A1 protein was expressed in E. coli and purified by using conventional chromatography.
Further Information:	Sequence: MAMVSEFLKQ AWFIENEEQE YVQTVKSSKG GPGSAVSPYP TFNPSSDVAA LHKAIMVKGV DEATIIDILT KRNNAQRQQI KAAYLQETGK PLDETLKKAL TGHLEEVVLA LLKTPAQFDA DELRAAMKGL GTDEDTLIEI LASRTNKEIR DINRVYREEL KRDLAKDITS DTSGDFRNAL LSLAKGDRSE DFGVNEDLAD SDARALYEAG ERRKGTDVNV FNTILTTRSY PQLRRVFQKY TKYSKHDMNK VLDLELKGDI EKCLTAIVKC ATSKPAFFAE KLHQAMKGVG TRHKALIRIM VSRSEIDMND IKAFYQKMYG ISLCQAILDE TKGDYEKILV ALCGGN
Synonym:	Annexin-1, Lipocortin I, Calpactin II, Chromobindin-9, p35, ANXA1, ANX1, LPC1, Annexin I, AnnexinA1, AnnexinI, ANX 1, ANX A1, ANXA 1, ANXA1 protein, CalpactinII, Chromobindin 9, Chromobindin9, HGNC:533, Lipocortin 1, Lipocortin I, Lipocortin1, LipocortinI, LPC 1, Phospholipase A2 inhibitory protein,
Ascension Number:	P04083
NCBI EntrezGene:	NP_000691
Shipping Conditions:	Ship on cold packs
Storage:	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Usage:	Research use only