| Applications: | ELISA, WB, ICC/IF |
| Species Reactivity: | Human |
| Isotype: | Mouse IgG2a kappa |
| Immunogen: | Recombinant human GCN5L2 (411-837aa) purified from E. coli |
| Purification: | By protein-A affinity chromatography |
| Conjugation: | Unconjugated |
| Description: | GCN5L2, as known as GCN5 and KAT2A is the use of immunoprecipitated GCN5L2 for acetylation toprovide the additional components important for acetylation. GCN5L2 can be one of the potential enzymesinvolved in acetylation in vivo. GCN5L2 is expressed predominantly in the embryo and newborn and is essentialfor normal embryonic development. Therefore, GCN5L2 appears to be important for differentiation ofembryonic-derived preadipocytes. On the one hand, loss of GCN5L2 leads to high incidence of apoptosis inthe GCN5L2 mutants that begins before the onset of morphological abnormality. |
| Further Information: | The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results |
| Synonym: | KAT2A, general control of amino-acid synthesis 5-like 2, GCN5, PCAF-b, K(lysine) acetyltransferase 2A, hGCN5L2,GCN5 |
| Ascension Number: | Q92830 |
| NCBI EntrezGene: | NP_066564 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
