Ordering Details
Cat Number:	ATGA0415-50ul
Size:	50uL
Concentration:	1 mg/mL
Price:	£123.00
Quantity:
Shipping:	£12.00

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GPD1L [AT14E2], Mouse Monoclonal Antibody

Partner: NKMax Bio (ATGen)

Applications:	ELISA, WB, ICC/IF
Species Reactivity:	Human
Isotype:	Mouse IgG1 kappa
Immunogen:	Recombinant human GPD1L (1-351aa) purified from E. coli
Purification:	By protein-A affinity chromatography
Conjugation:	Unconjugated
Description:	GPD1L is converts sn-glycerol 3-phosphate to glycerone phosphate. This protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). GPD1L is thought to affect trafficking of the cardiac sodium current to the cell surface. Mutations in GPD1L are the cause of sudden infant death syndrome (SIDS) and Brugada syndrome type 2, an autosomal dominant tachyarrhythmia.
Further Information:	The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Synonym:	Glycerol-3-phosphate dehydrogenase 1-like protein, GPD1-L
Ascension Number:	Q8N335
NCBI EntrezGene:	NP_055956
Shipping Conditions:	Ship on cold packs
Storage:	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Usage:	Research use only

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The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GPD1L antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.Lane 1. : MCF7 cell lysateLane 2. : 293T cell lysateLane 3. : Jurkat cell lysateLane 4 : SW480 cell lysateLane 5 : PC3 cell lysate The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GPD1L antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.Lane 1. : 293T cell lysateLane 2. : GPD1L Transfected 293T cell lysate

ICC/IF analysis of GPD1L in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human GPD1L antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).