| Applications: | ELISA, WB, ICC/IF, FACS |
| Species Reactivity: | Human |
| Isotype: | Mouse IgG2a kappa |
| Immunogen: | Recombinant human ALDOA (1-364aa) purified from E. coli |
| Purification: | By protein-A affinity chromatography |
| Conjugation: | Unconjugated |
| Description: | Aldolase (fructose bisphosphate aldolase), a glycolytic enzyme, catalyzes the conversion of fructose 1, 6-bisphosphate to 3-phosphoglyceraldehyde. This ubiquitous enzyme is present as three different isozymes: aldolase A, aldolase B, and aldolase C. Research studies suggest that aldolase A expression potentially differentiates between nonneoplastic liver diseases and hepatocarcinoma. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney, and intestine and similar to aldolase C levels in brain and other nervous tissue. |
| Further Information: | The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000. Recommended dilution range for ICC/IF and Flow cytometry is 1:200. |
| Synonym: | Fructose bisphosphate aldolase A, ALDOA, ALDA, GSD12, Fructose bisphosphate aldolase A Aldolase A, Aldolase A fructose bisphosphatase, Aldolase A fructose bisphosphate, Fructose 1 6 bisphosphate triosephosphate lyase, Fructose bisphosphate aldolase, Lung cancer antigen NY Lu 1, MGC10942, MGC17716, MGC17767, Muscle type aldolase, |
| Ascension Number: | P04075 |
| NCBI EntrezGene: | NP_908930 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
