Ordering Details
Cat Number:	ATGA0304-100ul
Size:	100uL
Concentration:	1mg/mL
Price:	£205.00
Quantity:
Shipping:	£12.00

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MSDS

Cathepsin Z [AT6G11], Mouse Monoclonal Antibody

Partner: NKMax Bio (ATGen)

Applications:	ELISA, WB, ICC/IF
Species Reactivity:	Human
Isotype:	Mouse IgG2b kappa
Immunogen:	Recombinant human CTSZ (62-303aa) purified from E. coli
Purification:	By protein-A affinity chromatography
Conjugation:	Unconjugated
Description:	CTSZ (Cathepsin Z), also known as Cathepsin X and Cathepsin P, is 303 amino acid protein. It is lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. This gene is widely expressed in cancer cell lines, primary tumors. CTSZ may be involved in tumor progression. And, CTSZ plays a role in normal intracellular protein degradation
Further Information:	The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
Synonym:	Cathepsin Z preproprotein, Cathepsin Z preproprotein, Cathepsin Z, CTSX
Ascension Number:	Q9UBR2
NCBI EntrezGene:	NP_001327
Shipping Conditions:	Ship on cold packs
Storage:	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Usage:	Research use only

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The cell lysates of HeLa (40ug) and SW480 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CTSZ antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.The recombinant proteins (20ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CTSZ antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.Lane 1. : Recombinant Human CTSBLane 2. : Recombinant Human CTSDLane 3. : Recombinant Human CTSELane 4. : Recombinant Human CTSFLane 5. : Recombinant Human CTSHLane 6. : Recombinant Human CTSKLane 7. : Recombinant Human CTSLLane 8. : Recombinant Human CTSSLane 9. : Recombinant Human CTSWLane 10. : Recombinant Human CTSZ

ICC/IF analysis of CTSZ in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CTSZ antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).