| Applications: | ELISA, WB |
| Species Reactivity: | Influenza A |
| Isotype: | Mouse IgG1 kappa |
| Immunogen: | Recombinant Influenza A H5N1/HA1 (17-338aa) purified from Baculovirus |
| Conjugation: | Unconjugated |
| Description: | H5N1 is a subtype of the species Influenza A virus of the Influenzavirus A genus of the Orthomyxoviridae family. consists of single-stranded eight-segment negative-sense genomic RNAs, helical viral ribonucleoprotein (RNP) complexes (RNA segments NP, PB2, PB1 and PA), three viral envelope proteins (hemagglutinin [HA], neuraminidase [NA], and M2 ion channel), and a maxtir (M1) protein. Influenza A viruses are further classified into 16 HA (H1-H16) and 9 NA (N1-N9) serotypes based on the antigenic characteristics of HA and NA envelope glycoproteins. It is responsible for binding the virus to the cell that is being infected. HA protein has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding of these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane. |
| Further Information: | The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:3000.;;;;ELISA;;H5N1 HA1 Antibody (1 ug/ml) specifically recognizes H5N1/HA1 recombinant protein, but not interacted H1N1/HA1 and H3N2/HA1 recombinant protein in ELISA. |
| Synonym: | Hemagglutinin, Influenza A virus (A/Vietnam/HN31242/2007H5N1) haemagglutinin |
| Ascension Number: | A9YU04 |
| NCBI EntrezGene: | ABY19417 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
