| Applications: | ELISA, WB, ICC/IF |
| Species Reactivity: | Human |
| Isotype: | Mouse IgG1 kappa |
| Immunogen: | Recombinant human 14-3-3 tau (1-245aa) purified from E. coli |
| Purification: | By protein-G affinity chromatography |
| Conjugation: | Unconjugated |
| Description: | The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau andtau that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis. |
| Further Information: | The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000. |
| Synonym: | tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein theta polypeptide, YWHAQ, 1C5, HS1, 14-3-3 tau, Tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide, tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein, theta polypeptide 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 14 3 3 tau, 14 3 3 theta, KCIP1, Protein HS1, Protein kinase C inhibitor protein 1, tyr3/trp5 monooxygenase activation protein, theta, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, theta polypeptide. |
| Ascension Number: | P27348 |
| NCBI EntrezGene: | NP_006817 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
