| Applications: | ELISA, WB, FACS, ICC/IF |
| Species Reactivity: | Human |
| Isotype: | Mouse IgG1 kappa |
| Immunogen: | Recombinant human EIF5A (1-154aa) purified from E. coli |
| Purification: | By protein-G affinity chromatography |
| Conjugation: | Unconjugated |
| Description: | Eukaryotic translation initiation factor 5A (eIF5A) is the only protein Known to contain unusual amino acid formed by the action of deoxyhypusine synthase and deoxyhypusine hydroxylase using spermidine as the substrate. This protein was previously reported to be involved in the first step of peptide bond formation in translation; however more recent work implicates it as a universally conserved translation elongation factor. Modulation of eIF5A has been linked to proliferation and cancer. |
| Further Information: | The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. |
| Synonym: | Eukaryotic translation initiation factor 5A isoform B, EIF-5A, EIF5A1, eIF5AI, Eukaryotic translation initiation factor 5A isoform B eIF 4D, EIF 5A, eIF 5A 1, eIF 5A1, eIF4D, uORF, uORF A, Eukaryotic initiation factor 5A, Rev binding factor, Eukaryotic initiation factor 5A isoform 1, MGC99547, Eukaryotic translation initiation factor 5A, Eukaryotic translation initiation factor 5A 1, MGC104255. |
| Ascension Number: | P63241 |
| NCBI EntrezGene: | NP_001961 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
