Ordering Details
Cat Number:	AP9003a-ev
Size:	80uL
Price:	£117.00
Quantity:
Shipping:	£12.00

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Data Sheet

MSDS

E2F5 [N-term] [RB23726], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:	FC, IHC-P, WB
Species Reactivity:	Human
Isotype:	Rabbit Ig
Purification:	Affinity Purified Rabbit Polyclonal Antibody
Description:	E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB.
Further Information:	This E2F5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human E2F5.
Synonym:	Transcription factor E2F5, E2F-5, E2F5
Ascension Number:	Q15329
NCBI EntrezGene:	1875
Shipping Conditions:	Ship on cold packs
Storage:	Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:	Research use only

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Anti-E2F5 Antibody (N-term) at 1:2000 dilution + HepG2 whole cell lysateLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDaBlocking/Dilution buffer: 5% NFDM/TBST.