| Applications: | WB, FC |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. |
| Further Information: | This BDK_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the Central region of human BDK_1. |
| Synonym: | B1 bradykinin receptor, B1R, BK-1 receptor, BDKRB1, BRADYB1 |
| Ascension Number: | P46663 |
| NCBI EntrezGene: | 623 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
