Ordering Details
Cat Number:	AP8141a-ev
Size:	80uL
Price:	£117.00
Quantity:
Shipping:	£12.00

Document Links

Data Sheet

MSDS

HK1 [Hexokinase] [N-term] [RB3921/RB3922], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:	WB, IHC-P-Leica
Species Reactivity:	Human, Rat
Isotype:	Rabbit Ig
Purification:	Purified Rabbit Polyclonal Antibody
Description:	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. The hexokinase gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of the hexokinase gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. HK1 encodes the ubiquitously expressed isoform. Its 5' end includes an exon which is unique to this transcript and which encodes a distinct N-terminus that contains the porin binding domain (PBD). The porin binding domain mediates association with the mitochondrial membrane.
Further Information:	This HK1 (Hexokinase) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-108 amino acids from the N-terminal region of human HK1 (Hexokinase).
Synonym:	Hexokinase-1, Brain form hexokinase, Hexokinase type I, HK I, HK1
Ascension Number:	P19367
NCBI EntrezGene:	3098
Shipping Conditions:	Ship on cold packs
Storage:	Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:	Research use only

Insight Biotechnology Ltd reserves the right to change pricing without notice

All lanes : Anti-HK1 (Hexokinase) Antibody (N-term) at 1:1000 dilutionLane 1: MCF-7 whole cell lysateLane 2: Rat brain lysateLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 110 kDaBlocking/Dilution buffer: 5% NFDM/TBST.