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Cat Number:AP8023d-ev
Size:80uL
Price:£117.00
Quantity:
Shipping:£12.00

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Data Sheet
MSDS

 

PI3KR1 [N-term L11] [RB11634], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:IF, WB, FC, IHC-P-Leica
Species Reactivity:Human, Rat
Isotype:Rabbit Ig
Purification:Purified Rabbit Polyclonal Antibody
Description:Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.
Further Information:This PI3KR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PI3KR1.
Synonym:Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PIK3R1, GRB1
Ascension Number:P27986
NCBI EntrezGene:5295
Shipping Conditions:Ship on cold packs
Storage:Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:Research use only

 

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Immunofluorescent analysis of 4% paraformaldehyde-fixed,  0. 1% Triton X-100 permeabilized Hela cells labeling PIK3R1 with AP8023d at 1/25 dilution, followed by Dylight� 488-conjugated goat anti-Rabbit IgG secondary antibody at 1/200 dilution (green). Immunofluorescence image showing  Nucleus and Weak Cytoplasm staining on Hela cell line.  Cytoplasmic actin is detected with Dylight� 554 Phalloidin(red). The nuclear counter stain is DAPI (blue).

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0. 1% Triton X-100 permeabilized Hela cells labeling PIK3R1 with AP8023d at 1/25 dilution, followed by Dylight� 488-conjugated goat anti-Rabbit IgG secondary antibody at 1/200 dilution (green). Immunofluorescence image showing Nucleus and Weak Cytoplasm staining on Hela cell line. Cytoplasmic actin is detected with Dylight� 554 Phalloidin(red). The nuclear counter stain is DAPI (blue).