Applications: | WB |
Species Reactivity: | Human, Mouse |
Isotype: | Rabbit Ig |
Purification: | Purified Rabbit Polyclonal Antibody |
Description: | ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. |
Further Information: | This ACE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1274-1306 amino acids from the C-terminal region of human ACE. |
Synonym: | Angiotensin-converting enzyme, ACE, 321-, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1 |
Ascension Number: | P12821 |
NCBI EntrezGene: | 1636 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |