| Applications: | FC, WB |
| Species Reactivity: | Human, Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Purified Rabbit Polyclonal Antibody |
| Description: | In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. |
| Further Information: | This HOXA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-223 amino acids from the C-terminal region of human HOXA5. |
| Synonym: | Homeobox protein Hox-A5, Homeobox protein Hox-1C, HOXA5, HOX1C |
| Ascension Number: | P20719 |
| NCBI EntrezGene: | 3202 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
