Ordering Details
Cat Number:	AP6414a
Size:	400uL
Price:	£304.00
Quantity:
Shipping:	£12.00

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Data Sheet

MSDS

Parkin [N-term] [RB8213], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:	WB
Species Reactivity:	Drosophila
Isotype:	Rabbit Ig
Purification:	Purified Rabbit Polyclonal Antibody
Description:	Parkin is thought to play a role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. Mutations in the human version of the protein are known to cause autosomal recessive juvenile parkinsonism.
Further Information:	This Drosophila Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the N-terminal region of human Drosophila Parkin.
Synonym:	CG10523-PB; isoform B; Cg10523-pc; isoform c; PARKIN; park; parkin;
Ascension Number:	Q7KTX7
NCBI EntrezGene:	40336
Shipping Conditions:	Ship on cold packs
Storage:	Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:	Research use only

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The anti-Drosophila Parkin Pab (Cat. #AP6414a) is used in Western blot to detect Drosophila Parkin in, from left to right, mouse kidney, mouse brain, mouse heart, Ramos, and Hela tissue lysates.