Applications: | WB |
Species Reactivity: | Mouse |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. |
Further Information: | This Cdc25A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Cdc25A. |
Synonym: | M-phase inducer phosphatase 1, Dual specificity phosphatase Cdc25A, CDC25A |
Ascension Number: | P30304 |
NCBI EntrezGene: | 993 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |