| Applications: | WB, FC, IHC-P |
| Species Reactivity: | Human, Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | The melanin-concentrating hormone (MCH) is a cyclicneuropeptide isolated initially from salmon pituitary gland andlater from rat hypothalamus (summarized by Nahon et al., 1992[PubMed 1572663]). In mammals, MCH perikarya are confined largelyto the lateral hypothalamus and zona incerta area with extensiveneuronal projections throughout the brain, including theneurohypophysis. The anatomic distribution suggests aneurotransmitter or neuromodulator role for MCH in a broad array ofneuronal functions directed toward the regulation of goal-directedbehavior, such as food intake, and general arousal. MCH and 2 otherputative neuropeptides, NEI and NGE, are encoded by the sameprecursor and appear colocalized in nerve cells and in manyinstances within the projections. The precursor is designatedpro-melanin-concentrating hormone (PMCH). |
| Further Information: | This PMCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the Central region of human PMCH. |
| Synonym: | Pro-MCH, Neuropeptide-glycine-glutamic acid, NGE, Neuropeptide G-E, Neuropeptide-glutamic acid-isoleucine, NEI, Neuropeptide E-I, Melanin-concentrating hormone, MCH, PMCH, MCH |
| Ascension Number: | P20382 |
| NCBI EntrezGene: | 5367 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
