| Applications: | FC, IHC-P, WB |
| Species Reactivity: | Human, Hamster |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | Functions of the cell cortex, including motility,adhesion, and cytokinesis, are mediated by the reorganization ofthe actin cytoskeleton and recent evidence suggests a role for theFormin homology (FH) proteins in these processes. The proteinencoded by this gene contains FH domains and belongs to a novel FHprotein subfamily implicated in cell polarity. Wnt/Fz signalingactivates the small GTPase Rho, a key regulator of cytoskeletonarchitecture, to control cell polarity and movement duringdevelopment. Activation requires Dvl-Rho complex formation, anassembly mediated by this gene product, which is thought tofunction as a scaffolding protein. Evidence of alternative splicinghas been observed for this gene but the full-length nature of thesevariants has not been determined. |
| Further Information: | This DAAM1-T361 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the N-terminal region of human DAAM1-T361. |
| Synonym: | Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666 |
| Ascension Number: | Q9Y4D1 |
| NCBI EntrezGene: | 23002 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
