Applications: | WB, FC |
Species Reactivity: | Human |
Isotype: | Rabbit IgG |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. |
Further Information: | This ADM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids of human ADM. |
Synonym: | ADM, Adrenomedullin, AM, Proadrenomedullin N-20 terminal peptide, ProAM N-terminal 20 peptide, PAMP, ProAM-N20, ADM, AM |
Ascension Number: | P35318 |
NCBI EntrezGene: | 133 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |