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Cat Number:AP3068a
Size:400uL
Price:£304.00
Quantity:
Shipping:£12.00

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Data Sheet
MSDS

 

p-CDK7 [Thr170] [RB07518], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:IHC-P, DB, WB
Species Reactivity:Human, Mouse
Isotype:Rabbit Ig
Purification:Affinity Purified Rabbit Polyclonal Antibody
Description:The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Further Information:This CDK7 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T170 of human CDK7.
Synonym:Cyclin-dependent kinase 7, 39 kDa protein kinase, p39 Mo15, CDK-activating kinase 1, Cell division protein kinase 7, Serine/threonine-protein kinase 1, TFIIH basal transcription factor complex kinase subunit, CDK7, CAK, CAK1, CDKN7, MO15, STK1
Ascension Number:P50613
NCBI EntrezGene:1022
Shipping Conditions:Ship on cold packs
Storage:Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:Research use only

 

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Western blot analysis of extracts from Hela and MCF-7 cells,  untreated or lamda phosphatase-treated,  using Phospho-CDK7(T170) Antibody (upper) or Beta-actin (lower).

Western blot analysis of extracts from Hela and MCF-7 cells, untreated or lamda phosphatase-treated, using Phospho-CDK7(T170) Antibody (upper) or Beta-actin (lower).