Ordering Details
Cat Number:	AP22372a
Size:	200uL
Price:	£304.00
Quantity:
Shipping:	£12.00

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Data Sheet

MSDS

TNIK[S764] [RB59089], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:	IHC-P-Leica, WB
Species Reactivity:	Human, Mouse
Isotype:	Rabbit IgG
Purification:	Purified Rabbit Polyclonal Antibody
Description:	Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
Further Information:	This TNIK(S764) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human TNIK(S764).
Synonym:	TRAF2 and NCK-interacting protein kinase, 2.7.11.1, TNIK, KIAA0551
Ascension Number:	Q9UKE5
NCBI EntrezGene:	23043
Shipping Conditions:	Ship on cold packs
Storage:	Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:	Research use only

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All lanes : Anti-TNIK(S764) Antibody at 1:500 dilutionLane 1: Human brain tissue lysateLane 2: Caco2 whole cell lysateLane 3: U-2 OS whole cell lysateLane 4: U-251 MG whole cell lysateLane 5: Mouse brain tissue lysateLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 155 kDaBlocking/Dilution buffer: 5% NFDM/TBST.