Applications: | WB |
Species Reactivity: | Human, Rat |
Isotype: | Rabbit Ig |
Purification: | Purified Rabbit Polyclonal Antibody |
Description: | Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. |
Further Information: | This EEF2k (Ser366) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 337-371 amino acids from human EEF2k. |
Synonym: | Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, 2.7.11.20, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, EEF2K |
Ascension Number: | O00418 |
NCBI EntrezGene: | 29904 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |