| Applications: | WB |
| Species Reactivity: | Zebrafish |
| Isotype: | Rabbit Ig |
| Purification: | Purified Rabbit Polyclonal Antibody |
| Description: | Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively (PubMed:<a href=http://www.uniprot.org/citations/24316148 target=_blank>24316148</a>, PubMed:<a href=http://www.uniprot.org/citations/24407481 target=_blank>24407481</a>). Acts redundantly with agtrl1b in heart development. |
| Further Information: | This aplnra antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 343-377 amino acids from the human region of aplnra. |
| Synonym: | Apelin receptor A, Angiotensin II receptor-like 1a, Angiotensin receptor-like 1a, G-protein coupled receptor APJ A, aplnra, agtrl1 {ECO:0000312|EMBL:ABI994701}, agtrl1a |
| Ascension Number: | Q7SZP9 |
| NCBI EntrezGene: | 561935 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
