Ordering Details
Cat Number:	AP20984c-ev
Size:	80uL
Price:	£117.00
Quantity:
Shipping:	£12.00

Document Links

Data Sheet

MSDS

EWSR1 [C-term] [RB51591], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:	WB, IF
Species Reactivity:	Human, Mouse
Isotype:	Rabbit Ig
Purification:	Purified Rabbit Polyclonal Antibody
Description:	Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Further Information:	This EWSR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 639-674 amino acids from the C-terminal region of human EWSR1.
Synonym:	RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS
Ascension Number:	Q01844
NCBI EntrezGene:	2130
Shipping Conditions:	Ship on cold packs
Storage:	Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:	Research use only

Insight Biotechnology Ltd reserves the right to change pricing without notice

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0. 1% Triton X-100 permeabilized Hela (Human Cervical epithelial adenocarcinoma cell line) cells labeling EWSR1 with AP20984c at 1/25 dilution, followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG (1583138) secondary antibody at 1/400 dilution (green). Confocal image showing nuclear staining on Hela cell line. Cytoplasmic actin is detected with Alexa Fluor� 555 conjugated with Phalloidin (OB16636430) at 1/100 dilution (red).