| Applications: | IHC-P-Leica, WB |
| Species Reactivity: | Human, Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | The galectins are a family of beta-galactoside-bindingproteins implicated in modulating cell-cell and cell-matrixinteractions. LGALS3BP has been found elevated in the serum ofpatients with cancer and in those infected by the humanimmunodeficiency virus (HIV). It appears to be implicated in immuneresponse associated with natural killer (NK) andlymphokine-activated killer (LAK) cell cytotoxicity. Usingfluorescence in situ hybridization the full length 90K cDNA hasbeen localized to chromosome 17q25. The native protein bindsspecifically to a human macrophage-associated lectin known as Mac-2and also binds galectin 1. |
| Further Information: | This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP. |
| Synonym: | Galectin-3-binding protein, Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, MAC2BP, Mac-2 BP, Tumor-associated antigen 90K, LGALS3BP, M2BP |
| Ascension Number: | Q08380 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
