| Species Reactivity: | C.Elegans |
| Isotype: | Rabbit Ig |
| Purification: | Purified Rabbit Polyclonal Antibody |
| Description: | The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing. |
| Further Information: | This Dcr-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1068-1097 amino acids of CAEEL Dcr-1. |
| Synonym: | Endoribonuclease dcr-1, 3126-, dcr-1 |
| Ascension Number: | P34529 |
| NCBI EntrezGene: | 176138 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
