Applications: | WB |
Species Reactivity: | Human |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | HERC3 belongs to the HERC family of ubiquitin ligases, allof which contain a HECT domain and at least 1 RCC1 (MIM179710)-like domain (RLD). The 350-amino acid HECT domain ispredicted to catalyze the formation of a thioester with ubiquitinbefore transferring it to a substrate, and the RLD is predicted toact as a guanine nucleotide exchange factor for small G proteins(Hochrainer et al., 2005 [PubMed 15676274]). |
Further Information: | This HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3. |
Synonym: | Probable E3 ubiquitin-protein ligase HERC3, 632-, HECT domain and RCC1-like domain-containing protein 3, HERC3, KIAA0032 |
Ascension Number: | Q15034 |
NCBI EntrezGene: | 8916 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |