| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene is a member of the H/ACA snoRNPs (smallnucleolar ribonucleoproteins) gene family. snoRNPs are involved invarious aspects of rRNA processing and modification and have beenclassified into two families: C/D and H/ACA. The H/ACA snoRNPs alsoinclude the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNPproteins localize to the dense fibrillar components of nucleoli andto coiled (Cajal) bodies in the nucleus. Both 18S rRNA productionand rRNA pseudouridylation are impaired if any one of the fourproteins is depleted. These four H/ACA snoRNP proteins are alsocomponents of the telomerase complex. The encoded protein of thisgene contains two glycine- and arginine-rich domains and is relatedto Saccharomyces cerevisiae Gar1p. Two splice variants have beenfound for this gene. |
| Further Information: | This GAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human GAR1. |
| Synonym: | H/ACA ribonucleoprotein complex subunit 1, Nucleolar protein family A member 1, snoRNP protein GAR1, GAR1, NOLA1 |
| Ascension Number: | Q9NY12 |
| NCBI EntrezGene: | 54433 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
