| Applications: | WB |
| Species Reactivity: | Human, Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene encodes a member of the cyclin family. Cyclinsare important regulators of cell cycle transitions through theirability to bind and activate cyclin-dependent protein kinases. Thismember also belongs to the F-box protein family which ischaracterized by an approximately 40 amino acid motif, the F-box.The F-box proteins constitute one of the four subunits of theubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. TheF-box proteins are divided into 3 classes: Fbws containing WD-40domains, Fbls containing leucine-rich repeats, and Fbxs containingeither different protein-protein interaction modules or norecognizable motifs. The protein encoded by this gene belongs tothe Fbxs class and it was one of the first proteins in which theF-box motif was identified. |
| Further Information: | This CCNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-524 amino acids from the Central region of human CCNF. |
| Synonym: | Cyclin-F, F-box only protein 1, CCNF, FBX1, FBXO1 |
| Ascension Number: | P41002 |
| NCBI EntrezGene: | 899 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
