| Applications: | WB |
| Species Reactivity: | Human, Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene encodes aGDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase whichis localized to the cytosolic side of the endoplasmic reticulum(ER) and catalyzes the transfer of the fourth and fifth mannoseresidue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol andMan4GlcNAc2-PP-dolichol resulting in the production ofMan5GlcNAc2-PP-dolichol. Mutations in this gene are associated withcongenital disorder of glycosylation type Ip (CDGIP). This geneoverlaps but is distinct from the UTP14, U3 small nucleolarribonucleoprotein, homolog C (yeast) gene. A pseudogene of theGDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase hasbeen identified on chromosome 19. |
| Further Information: | This ALG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-468 amino acids from the C-terminal region of human ALG11. |
| Synonym: | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase, ALG11, GT8 |
| Ascension Number: | Q2TAA5 |
| NCBI EntrezGene: | 440138 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
