| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | Acetyl-CoA carboxylase (ACC) is a complex multifunctionalenzyme system. ACC is a biotin-containing enzyme which catalyzesthe carboxylation of acetyl-CoA to malonyl-CoA, the rate-limitingstep in fatty acid synthesis. There are two ACC forms, alpha andbeta, encoded by two different genes. ACC-alpha is highly enrichedin lipogenic tissues. The enzyme is under long term control at thetranscriptional and translational levels and under short termregulation by the phosphorylation/dephosphorylation of targetedserine residues and by allosteric transformation by citrate orpalmitoyl-CoA. Multiple alternatively spliced transcript variantsdivergent in the 5' sequence and encoding distinct isoforms havebeen found for this gene. |
| Further Information: | This ACACA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2010-2039 amino acids from the C-terminal region of human ACACA. |
| Synonym: | Acetyl-CoA carboxylase 1, ACC1, ACC-alpha, Biotin carboxylase, ACACA, ACAC, ACC1, ACCA |
| Ascension Number: | Q13085 |
| NCBI EntrezGene: | 31 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
