Applications: | WB |
Species Reactivity: | Human |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L1P family of ribosomal proteins. It is located in thecytoplasm. The expression of this gene is downregulated in thethymus by cyclosporin-A (CsA), an immunosuppressive drug. Studiesin mice have shown that the expression of the ribosomal proteinL10a gene is downregulated in neural precursor cells duringdevelopment. This gene previously was referred to as NEDD6 (neuralprecursor cell expressed, developmentally downregulated 6), but ithas been renamed RPL10A (ribosomal protein 10a). As is typical forgenes encoding ribosomal proteins, there are multiple processedpseudogenes of this gene dispersed through the genome. [provided byRefSeq]. |
Further Information: | This RPL10A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-31 amino acids from the N-terminal region of human RPL10A. |
Synonym: | 60S ribosomal protein L10a, CSA-19, Neural precursor cell expressed developmentally down-regulated protein 6, NEDD-6, RPL10A, NEDD6 |
Ascension Number: | P62906 |
NCBI EntrezGene: | 4736 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |