| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | CpG methylation is an epigenetic modification that isimportant for embryonic development, imprinting, and X-chromosomeinactivation. Studies in mice have demonstrated that DNAmethylation is required for mammalian development. This geneencodes a DNA methyltransferase that is thought to function in denovo methylation, rather than maintenance methylation. The proteinlocalizes to the cytoplasm and nucleus and its expression isdevelopmentally regulated. Alternative splicing results in multipletranscript variants encoding different isoforms. [provided byRefSeq]. |
| Further Information: | This DNMT3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 872-900 amino acids from the C-terminal region of human DNMT3A. |
| Synonym: | DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, MHsaIIIA, DNMT3A |
| Ascension Number: | Q9Y6K1 |
| NCBI EntrezGene: | 1788 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
