| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene encodes a member of the MutT family ofnucleotide pyrophosphatases, a subset of the larger NUDIX hydrolasefamily. The gene product possesses a modification of the MutTsequence motif found in certain nucleotide pyrophosphatases. Theenzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and isresponsible for maintaining the intracellular level of thedinucleotide Ap4A, the function of which has yet to be established.This gene may be a candidate tumor suppressor gene. Alternativesplicing has been observed at this locus and three transcriptvariants, all encoding the same protein, have been identified. |
| Further Information: | This NUDT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the Central region of human NUDT2. |
| Synonym: | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2, NUDT2, APAH1 |
| Ascension Number: | P50583 |
| NCBI EntrezGene: | 318 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
