| Applications: | WB |
| Species Reactivity: | Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene encodes a 42.6 kD subunit of dynactin, amacromolecular complex consisting of 10-11 subunits ranging in sizefrom 22 to 150 kD. Dynactin binds to both microtubules andcytoplasmic dynein. It is involved in a diverse array of cellularfunctions, including ER-to-Golgi transport, the centripetalmovement of lysosomes and endosomes, spindle formation, chromosomemovement, nuclear positioning, and axonogenesis. This subunit ispresent in 8-13 copies per dynactin molecule, and is the mostabundant molecule in the dynactin complex. It is an actin-relatedprotein, and is approximately 60% identical at the amino acid levelto conventional actin. |
| Further Information: | This ACTR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human ACTR1A. |
| Synonym: | Alpha-centractin, Centractin, ARP1, Actin-RPV, Centrosome-associated actin homolog, ACTR1A, CTRN1 |
| Ascension Number: | P61163 |
| NCBI EntrezGene: | 10121 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
