| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | The protein encoded by this gene is an integral componentof Cajal bodies (also called coiled bodies). Cajal bodies arenuclear suborganelles of varying number and composition that areinvolved in the post-transcriptional modification of small nuclearand small nucleolar RNAs. The N-terminus of the coilin proteindirects its self-oligomerization while the C-terminus influencesthe number of nuclear bodies assembled per cell. Differentialmethylation and phosphorylation of coilin likely influences itslocalization among nuclear bodies and the composition and assemblyof Cajal bodies. This gene has pseudogenes on chromosome 4 andchromosome 14. |
| Further Information: | This COIL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human COIL. |
| Synonym: | Coilin, p80-coilin, COIL, CLN80 |
| Ascension Number: | P38432 |
| NCBI EntrezGene: | 8161 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
